Intel Education: Showing Evidence Tool: Your Genes


	Showing Evidence Tool: What's in Your Genes? Resources

Materials and Resources
Printed Materials
Magazine Articles

Multiple authors. (2003, April 11). Building on the DNA revolution. Science, several articles discussing the completion of the Human Genome Project.
Multiple authors. (2003, April 24). DNA 50th anniversary: Double helix at 50. Nature, several articles discussing the completion of the Human Genome Project.

Supplies
Kiwi DNA Lab:

Ziplock bags (1 per student pair)
Strainer or funnel (1 per 10 students)
Jar or beaker that fits strainer or funnel (1 per 10 students)
Cheese cloth (cut to cover the funnel)
Ice water bath (a large mixing bowl works well) (1 per 4–6 students)
Extraction solution (1 tube of 20 ml. per student pair)
Kiwifruit (cut into 12 pieces, each student pair needs 6 pieces)
Cold 95% ethanol or isopropanol (3–4 ml. per student)
Small test tubes (1 per student)

Dye Gel Electrophoresis Lab:

1 x TBE
Agarose
Various dye mixtures: Methyl Orange, Bromophenol Blue, Xylene Cyanol, Pyronin Y, Safranin O, Unknown (1 each per group)
Practice loading dye (above)
Micropipets and tips to load dye samples (6 per group)
Small microcentrifuge tubes (0.5 ml. or 0.65 ml. size) (6 per group)
Electrophoresis units and power supplies (1 per group)
1 x TBE for electrophoresis units
Microwave oven
Hot water bath for keeping agarose liquified

Who’s Your Daddy? Lab:

DNA from Mother (#1), Luna (#2), male whale A (#3), male whale B (#4) (1 per group)
Agarose
Tris-acetate/EDTA solution (TAE)
Micropipette/tips (4 per group)
Electrophoresis apparatus (1 per group)
Methyl blue stain
Light box (1 per group) Internet

Resources

The Human Genome Project Kit
www.nhgri.nih.gov/educationkit*
Includes a video, multimedia CD-ROM, and tips for using the kit in your classroom
DNA: Heredity & Beyond
http://library.thinkquest.org/20830/main.htm*
A 1998 ThinkQuest that gives background information regarding DNA, scientists, and related scientific discoveries as well as discusses ethical issues surrounding the manipulation of DNA
Genetic Disorder Information on the Web
www.ornl.gov/TechResources/Human_Genome/posters/chromosome/diseaseindex.html*
Database linking to genetic disorders found on each individual chromosome
Chromosome Viewer
www.ornl.gov/TechResources/Human_Genome/posters/chromosome/chooser.html*
Visual chromosome map of all 23 chromosome types with links to genetic diseases/disorders found on each individual chromosome
Gene Testing
www.ornl.gov/TechResources/Human_Genome/medicine/genetest.html*
Includes a description of gene testing along with pros and cons
Genetics in the Courtroom
www.ornl.gov/TechResources/Human_Genome/courts/courts.html*
Background and implications of using genetics in the courtroom
Ethical, Legal, Social, Implications of Human Genome Project
www.kumc.edu/gec/prof/geneelsi.html*
Links to several sites that involve controversial biotechnology issues and usages
Biotech Program (University of Arizona)
http://biotech.biology.arizona.edu/labs/labs.html*
Labs used in unit: Kiwi DNA Extraction, Agarose Gel Electrophoresis with Biological Dyes, DNA Fingerprinting: Whale Pod DNA
Biology Project (University of Arizona)
www.biology.arizona.edu*
Tutorials in both English and Spanish

Other Resources

Niccol, A. (Director). (1997). Gattaca. [VHS/DVD]. Los Angeles, CA: Columbia Pictures/Jersey Films.

Technology—Hardware

Computer with Internet to access the Showing Evidence Tool
Projection system to show students how to use the Showing Evidence Tool
VCR or DVD player to play Gattaca and Humane Genome video

Technology—Software

Word processing software to create biotechnology bills

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